Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn

نویسندگان

  • K Bragstad
  • M K Skram
  • H Dahl
  • P K Knudsen
  • M S Chawla
  • M Holberg - Petersen
  • K Vainio
  • S G Dudman
  • A M Kran
  • A E Rojahn
چکیده

H C Pfeiffer ([email protected])1, K Bragstad2, M K Skram1, H Dahl1, P K Knudsen1, M S Chawla3, M Holberg-Petersen4, K Vainio2, S G Dudman2, A M Kran4, A E Rojahn1 1. Department of Paediatrics, Oslo University Hospital, Oslo, Norway 2. Department of Virology, Norwegian Institute of Public Health, Oslo, Norway 3. Department of Radiology, Oslo University Hospital, Oslo, Norway 4. Department of Microbiology, Oslo University Hospital, University of Oslo, Institute of Clinical Medicine, Oslo, Norway

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منابع مشابه

Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn 2014.

Enterovirus D68 (EV-D68), phylogenetic clade B was identified in nasopharyngeal specimens of two cases of severe acute flaccid myelitis. The cases were six and five years-old and occurred in September and November 2014. EV-D68 is increasingly associated with acute flaccid myelitis in children, most cases being reported in the United States. Awareness of this possible neurological complication o...

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A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study.

BACKGROUND Enterovirus D68 was implicated in a widespread outbreak of severe respiratory illness across the USA in 2014 and has also been reported sporadically in patients with acute flaccid myelitis. We aimed to investigate the association between enterovirus D68 infection and acute flaccid myelitis during the 2014 enterovirus D68 respiratory outbreak in the USA. METHODS Patients with acute ...

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Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014

During August 8, 2014-October 14, 2014, a total of 11 children with acute flaccid myelitis and distinctive neuroimaging changes were identified near Denver, Colorado, USA. A respiratory prodrome was experienced by 10, and nasopharyngeal specimens were positive for enterovirus D68 (EV-D68) for 4. To determine whether an association exists between EV-D68 infection and acute flaccid myelitis, we c...

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High frequency of enterovirus D68 in children hospitalised with respiratory illness in Norway, autumn 2014

OBJECTIVES An unexpectedly high proportion of children were admitted for severe respiratory infections at the Oslo University Hospital, Ullevål, Norway, during September and October, 2014. In light of the ongoing outbreak of enterovirus-D68 (EV-D68) in North America a real-time RT-PCR for screening of enterovirus and enterovirus D68 was established. DESIGN We developed a duplex real-time RT-P...

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Re-analysis of metagenomic sequences from acute flaccid myelitis patients reveals alternatives to enterovirus D68

Metagenomic sequence data can be used to detect the presence of infectious viruses and bacteria, but normal microbial flora make this process challenging. We re-analyzed metagenomic RNA sequence data collected during a recent outbreak of acute flaccid myelitis (AFM), caused in some cases by infection with enterovirus D68. We found that among the patients whose symptoms were previously attribute...

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تاریخ انتشار 2015